Protein-ligand Complex:
Protein (PDB ID: 2pog - Variant: EA419D)
& Ligand (ChEMBL ID: CHEMBL2011418)

GUID

https://w3id.org/psnpbind/variant/182/ligand/CHEMBL2011418

PDB ID

2pog

Variant Type

EA419D

Ligand ID (ChEMBL ID)

CHEMBL2011418

Ligand Similarity* to the one in the experimentally obtained structure of the 2pog complex


* Tanimoto similarity obtained from the comparison of the FP2 fingerprint of the ligands, calculated using OpenBabel
0.628205

Binding Affinity

  • Conformer 1: -10.0 Kcal/Mol

Binding Affiniy against the Wild-type protein

WT Conformer 1: -9.7 Kcal/Mol