PSnpBind - Pocket SNPs effect on protein-ligand binding affinity

GUID	https://w3id.org/psnpbind/variant/587/ligand/CHEMBL1178326
PDB ID	3fv1
Variant Type	IA523V
Ligand ID (ChEMBL ID)	CHEMBL1178326
Ligand Similarity* to the one in the experimentally obtained structure of the 3fv1 complex * Tanimoto similarity obtained from the comparison of the FP2 fingerprint of the ligands, calculated using OpenBabel	0.61039
Binding Affinity	Conformer 1: -4.5 Kcal/Mol Conformer 2: -4.5 Kcal/Mol Conformer 3: -4.4 Kcal/Mol
Binding Affiniy against the Wild-type protein