PSnpBind - Pocket SNPs effect on protein-ligand binding affinity

GUID	https://w3id.org/psnpbind/variant/650/ligand/CHEMBL41326
PDB ID	3udh
Variant Type	GA230S
Ligand ID (ChEMBL ID)	CHEMBL41326
Ligand Similarity* to the one in the experimentally obtained structure of the 3udh complex * Tanimoto similarity obtained from the comparison of the FP2 fingerprint of the ligands, calculated using OpenBabel	0.701031
Binding Affinity	Conformer 1: -5.7 Kcal/Mol Conformer 2: -5.5 Kcal/Mol Conformer 3: -5.5 Kcal/Mol
Binding Affiniy against the Wild-type protein
WT	Conformer 1: -5.6 Kcal/Mol