PSnpBind - Pocket SNPs effect on protein-ligand binding affinity

GUID	https://w3id.org/psnpbind/variant/91/ligand/CHEMBL372243
PDB ID	2y5h
Variant Type	KA96R
Ligand ID (ChEMBL ID)	CHEMBL372243
Ligand Similarity* to the one in the experimentally obtained structure of the 2y5h complex * Tanimoto similarity obtained from the comparison of the FP2 fingerprint of the ligands, calculated using OpenBabel	0.625
Binding Affinity	Conformer 1: -6.7 Kcal/Mol Conformer 2: -6.7 Kcal/Mol Conformer 3: -6.3 Kcal/Mol
Binding Affiniy against the Wild-type protein
WT	Conformer 1: -7.0 Kcal/Mol